An Enhanced Hybrid Screening Approach to Identify Potent Inhibitors for the SARS-CoV-2 Main Protease From the NCI Compound Library

The emergence and rapid spread of SARS-CoV-2, the pathogen of COVID-19, have caused a worldwide public health crisis. The SARS-CoV-2 main protease (Mpro) is an essential enzyme for the virus and therefore an appealing target for the development of antivirals to treat COVID-19 patients. Recently, man...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Shuhua G., Yang, Kai S., Blankenship, Lauren R., Cho, Chia-Chuan D., Xu, Shiqing, Wang, Hongbin, Liu, Wenshe Ray
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8892251/
https://www.ncbi.nlm.nih.gov/pubmed/35252116
http://dx.doi.org/10.3389/fchem.2022.816576

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8892251/
https://www.ncbi.nlm.nih.gov/pubmed/35252116
http://dx.doi.org/10.3389/fchem.2022.816576

Ejemplares similares