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An Enhanced Hybrid Screening Approach to Identify Potent Inhibitors for the SARS-CoV-2 Main Protease From the NCI Compound Library

The emergence and rapid spread of SARS-CoV-2, the pathogen of COVID-19, have caused a worldwide public health crisis. The SARS-CoV-2 main protease (Mpro) is an essential enzyme for the virus and therefore an appealing target for the development of antivirals to treat COVID-19 patients. Recently, man...

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Detalles Bibliográficos
Autores principales:	Li, Shuhua G., Yang, Kai S., Blankenship, Lauren R., Cho, Chia-Chuan D., Xu, Shiqing, Wang, Hongbin, Liu, Wenshe Ray
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8892251/ https://www.ncbi.nlm.nih.gov/pubmed/35252116 http://dx.doi.org/10.3389/fchem.2022.816576

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