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Amino acid starvation‐induced LDLR trafficking accelerates lipoprotein endocytosis and LDL clearance

Mammalian cells utilize Akt‐dependent signaling to deploy intracellular Glut4 toward cell surface to facilitate glucose uptake. Low‐density lipoprotein receptor (LDLR) is the cargo receptor mediating endocytosis of apolipoprotein B‐containing lipoproteins. However, signaling‐controlled regulation of...

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Detalles Bibliográficos
Autores principales: Chen, Ye, Wu, Xiao, Zhang, Jing, Pan, Guopin, Wang, Xiaoyun, Guo, Xiaosun, Wang, Jianli, Cui, Xiaopei, Gao, Haiqing, Cheng, Mei, Yang, Jingwen, Zhang, Cheng, Jiang, Fan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8892268/
https://www.ncbi.nlm.nih.gov/pubmed/34994492
http://dx.doi.org/10.15252/embr.202153373