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APOE and KLF14 genetic variants are sex-specific for low high-density lipoprotein cholesterol identified by a genome-wide association study

To demonstrate the loci that relate to high-density lipoprotein cholesterol (HDL-C) levels and genetic sex heterogeneity, we enrolled 41,526 participants aged between 30 and 70 years old from the Taiwan Biobank in a genome-wide association study. We applied the Manhattan plot to display the p-values...

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Detalles Bibliográficos
Autores principales: Lee, Ying-Hui, Chang, Ya-Sian, Hsieh, Chih-Chang, Wang, Rong-Tsorng, Chang, Jan-Gowth, Chen, Chung-Jen, Chang, Shun-Jen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Genética 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8892272/
https://www.ncbi.nlm.nih.gov/pubmed/35238325
http://dx.doi.org/10.1590/1678-4685-GMB-2021-0280