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Heritable changes in division speed accompany the diversification of single T cell fate

Rapid clonal expansion of antigen-specific T cells is a fundamental feature of adaptive immune responses. It enables the outgrowth of an individual T cell into thousands of clonal descendants that diversify into short-lived effectors and long-lived memory cells. Clonal expansion is thought to be pro...

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Detalles Bibliográficos
Autores principales: Plambeck, Marten, Kazeroonian, Atefeh, Loeffler, Dirk, Kretschmer, Lorenz, Salinno, Ciro, Schroeder, Timm, Busch, Dirk H., Flossdorf, Michael, Buchholz, Veit R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8892279/
https://www.ncbi.nlm.nih.gov/pubmed/35217611
http://dx.doi.org/10.1073/pnas.2116260119