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Landscape of surfaceome and endocytome in human glioma is divergent and depends on cellular spatial organization

Therapeutic strategies directed at the tumor surfaceome (TS), including checkpoint inhibitor blocking antibodies, antibody drug conjugates (ADCs), and chimeric antigen receptor T (CAR-T) cells, provide a new armament to fight cancer. However, a remaining bottleneck is the lack of strategies to compr...

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Detalles Bibliográficos
Autores principales: Governa, Valeria, Talbot, Hugo, Gonçalves de Oliveira, Kelin, Cerezo-Magaña, Myriam, Bång-Rudenstam, Anna, Johansson, Maria C., Månsson, Ann-Sofie, Forsberg-Nilsson, Karin, Marko-Varga, György, Enríquez Pérez, Julio, Darabi, Anna, Malmström, Johan, Bengzon, Johan, Welinder, Charlotte, Belting, Mattias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8892282/
https://www.ncbi.nlm.nih.gov/pubmed/35217608
http://dx.doi.org/10.1073/pnas.2114456119