Precision targeting tumor cells using cancer-specific InDel mutations with CRISPR-Cas9

An ideal cancer therapeutic strategy involves the selective killing of cancer cells without affecting the surrounding normal cells. However, researchers have failed to develop such methods for achieving selective cancer cell death because of shared features between cancerous and normal cells. In thi...

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Detalles Bibliográficos
Autores principales: Kwon, Taejoon, Ra, Jae Sun, Lee, Soyoung, Baek, In-Joon, Khim, Keon Woo, Lee, Eun A, Song, Eun Kyung, Otarbayev, Daniyar, Jung, Woojae, Park, Yong Hwan, Wie, Minwoo, Bae, Juyoung, Cheng, Himchan, Park, Jun Hong, Kim, Namwoo, Seo, Yuri, Yun, Seongmin, Kim, Ha Eun, Moon, Hyo Eun, Paek, Sun Ha, Park, Tae Joo, Park, Young Un, Rhee, Hwanseok, Choi, Jang Hyun, Cho, Seung Woo, Myung, Kyungjae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8892319/
https://www.ncbi.nlm.nih.gov/pubmed/35217600
http://dx.doi.org/10.1073/pnas.2103532119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8892319/
https://www.ncbi.nlm.nih.gov/pubmed/35217600
http://dx.doi.org/10.1073/pnas.2103532119

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