A deep eutectic-based, self-emulsifying subcutaneous depot system for apomorphine therapy in Parkinson’s disease

Apomorphine, a dopamine agonist, is a highly effective therapeutic to prevent intermittent off episodes in advanced Parkinson’s disease. However, its short systemic half-life necessitates three injections per day. Such a frequent dosing regimen imposes a significant compliance challenge, especially...

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Detalles Bibliográficos
Autores principales: Kim, Jayoung, Gao, Yongsheng, Zhao, Zongmin, Rodrigues, Danika, Tanner, Eden E. L., Ibsen, Kelly, Sasmal, Pradip K., Jaladi, Rajasekhar, Alikunju, Shanavas, Mitragotri, Samir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Physical Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8892321/
https://www.ncbi.nlm.nih.gov/pubmed/35197281
http://dx.doi.org/10.1073/pnas.2110450119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8892321/
https://www.ncbi.nlm.nih.gov/pubmed/35197281
http://dx.doi.org/10.1073/pnas.2110450119

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