Cargando…
A DNA repair-independent role for alkyladenine DNA glycosylase in alkylation-induced unfolded protein response
Alkylating agents damage DNA and proteins and are widely used in cancer chemotherapy. While cellular responses to alkylation-induced DNA damage have been explored, knowledge of how alkylation affects global cellular stress responses is sparse. Here, we examined the effects of the alkylating agent me...
Autores principales: | , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8892324/ https://www.ncbi.nlm.nih.gov/pubmed/35197283 http://dx.doi.org/10.1073/pnas.2111404119 |