PRDM9 losses in vertebrates are coupled to those of paralogs ZCWPW1 and ZCWPW2

In most mammals and likely throughout vertebrates, the gene PRDM9 specifies the locations of meiotic double strand breaks; in mice and humans at least, it also aids in their repair. For both roles, many of the molecular partners remain unknown. Here, we take a phylogenetic approach to identify genes...

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Detalles Bibliográficos
Autores principales: Cavassim, Maria Izabel A., Baker, Zachary, Hoge, Carla, Schierup, Mikkel H., Schumer, Molly, Przeworski, Molly
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8892340/
https://www.ncbi.nlm.nih.gov/pubmed/35217607
http://dx.doi.org/10.1073/pnas.2114401119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8892340/
https://www.ncbi.nlm.nih.gov/pubmed/35217607
http://dx.doi.org/10.1073/pnas.2114401119

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