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PRDM9 losses in vertebrates are coupled to those of paralogs ZCWPW1 and ZCWPW2
In most mammals and likely throughout vertebrates, the gene PRDM9 specifies the locations of meiotic double strand breaks; in mice and humans at least, it also aids in their repair. For both roles, many of the molecular partners remain unknown. Here, we take a phylogenetic approach to identify genes...
Autores principales: | Cavassim, Maria Izabel A., Baker, Zachary, Hoge, Carla, Schierup, Mikkel H., Schumer, Molly, Przeworski, Molly |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8892340/ https://www.ncbi.nlm.nih.gov/pubmed/35217607 http://dx.doi.org/10.1073/pnas.2114401119 |
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