BIN1 modulation in vivo rescues dynamin-related myopathy

The mechanoenzyme dynamin 2 (DNM2) is crucial for intracellular organization and trafficking. DNM2 is mutated in dominant centronuclear myopathy (DNM2-CNM), a muscle disease characterized by defects in organelle positioning in myofibers. It remains unclear how the in vivo functions of DNM2 are regul...

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Detalles Bibliográficos
Autores principales: Lionello, Valentina Maria, Kretz, Christine, Edelweiss, Evelina, Crucifix, Corinne, Gómez-Oca, Raquel, Messaddeq, Nadia, Buono, Suzie, Koebel, Pascale, Massana Muñoz, Xènia, Diedhiou, Nadège, Cowling, Belinda S., Bitoun, Marc, Laporte, Jocelyn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8892365/
https://www.ncbi.nlm.nih.gov/pubmed/35217605
http://dx.doi.org/10.1073/pnas.2109576119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8892365/
https://www.ncbi.nlm.nih.gov/pubmed/35217605
http://dx.doi.org/10.1073/pnas.2109576119

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