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Nanogels with High Loading of Anesthetic Nanocrystals for Extended Duration of Sciatic Nerve Block

[Image: see text] The development of thermoresponsive nanogels loaded with nanocrystals of the local anesthetic bupivacaine nanocrystals (BNCs) for prolonged peripheral nerve pain relief is reported here. BNCs were prepared using the antisolvent precipitation method from the hydrophobic form of bupi...

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Detalles Bibliográficos
Autores principales: Alejo, Teresa, Uson, Laura, Landa, Guillermo, Prieto, Martin, Yus Argón, Cristina, Garcia-Salinas, Sara, de Miguel, Ricardo, Rodríguez-Largo, Ana, Irusta, Silvia, Sebastian, Victor, Mendoza, Gracia, Arruebo, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8892441/
https://www.ncbi.nlm.nih.gov/pubmed/33821601
http://dx.doi.org/10.1021/acsami.1c00894