Switchable assembly and function of antibody complexes in vivo using a small molecule

The antigen specificity and long serum half-life of monoclonal antibodies have made them a critical part of modern therapeutics. These properties have been coopted in a number of synthetic formats, such as antibody–drug conjugates, bispecific antibodies, or Fc-fusion proteins to generate novel biolo...

Descripción completa

Detalles Bibliográficos
Autores principales: Martinko, Alexander J., Simonds, Erin F., Prasad, Suchitra, Ponce, Alberto, Bracken, Colton J., Wei, Junnian, Wang, Yung-Hua, Chow, Tiffany-Lynn, Huang, Zhong, Evans, Michael J., Wells, James A., Hill, Zachary B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8892515/
https://www.ncbi.nlm.nih.gov/pubmed/35210365
http://dx.doi.org/10.1073/pnas.2117402119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8892515/
https://www.ncbi.nlm.nih.gov/pubmed/35210365
http://dx.doi.org/10.1073/pnas.2117402119

Ejemplares similares