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zMADM (zebrafish mosaic analysis with double markers) for single-cell gene knockout and dual-lineage tracing

As a vertebrate model organism, zebrafish has many unique advantages in developmental studies, regenerative biology, and disease modeling. However, tissue-specific gene knockout in zebrafish is challenging due to technical difficulties in making floxed alleles. Even when successful, tissue-level kno...

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Detalles Bibliográficos
Autores principales: Xu, Bing, Kucenas, Sarah, Zong, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8892518/
https://www.ncbi.nlm.nih.gov/pubmed/35197298
http://dx.doi.org/10.1073/pnas.2122529119