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zMADM (zebrafish mosaic analysis with double markers) for single-cell gene knockout and dual-lineage tracing
As a vertebrate model organism, zebrafish has many unique advantages in developmental studies, regenerative biology, and disease modeling. However, tissue-specific gene knockout in zebrafish is challenging due to technical difficulties in making floxed alleles. Even when successful, tissue-level kno...
Autores principales: | Xu, Bing, Kucenas, Sarah, Zong, Hui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8892518/ https://www.ncbi.nlm.nih.gov/pubmed/35197298 http://dx.doi.org/10.1073/pnas.2122529119 |
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