Role of ubiquitin-protein ligase UBR5 in the disassembly of mitotic checkpoint complexes

The mitotic (or spindle assembly) checkpoint system ensures accurate chromosome segregation in mitosis by preventing the onset of anaphase until correct bipolar attachment of sister chromosomes to the mitotic spindle is attained. It acts by promoting the assembly of a mitotic checkpoint complex (MCC...

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Detalles Bibliográficos
Autores principales: Kaisari, Sharon, Miniowitz-Shemtov, Shirly, Sitry-Shevah, Danielle, Shomer, Pnina, Kozlov, Guennadi, Gehring, Kalle, Hershko, Avram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8892521/
https://www.ncbi.nlm.nih.gov/pubmed/35217622
http://dx.doi.org/10.1073/pnas.2121478119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8892521/
https://www.ncbi.nlm.nih.gov/pubmed/35217622
http://dx.doi.org/10.1073/pnas.2121478119

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