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Role of ubiquitin-protein ligase UBR5 in the disassembly of mitotic checkpoint complexes
The mitotic (or spindle assembly) checkpoint system ensures accurate chromosome segregation in mitosis by preventing the onset of anaphase until correct bipolar attachment of sister chromosomes to the mitotic spindle is attained. It acts by promoting the assembly of a mitotic checkpoint complex (MCC...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8892521/ https://www.ncbi.nlm.nih.gov/pubmed/35217622 http://dx.doi.org/10.1073/pnas.2121478119 |