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Indigo plant leaf extract inhibits the binding of SARS-CoV-2 spike protein to angiotensin-converting enzyme 2

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) uses its S1 spike protein to bind to angiotensin-converting enzyme 2 (ACE2) on human cells in the first step of cell entry. Tryptanthrin, extracted from leaves of the indigo plant, Polygonum tinctorium, using d-limonene (17.3 µg/ml), is co...

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Detalles Bibliográficos
Autores principales: Hagiyama, Man, Takeuchi, Fuka, Sugano, Aki, Yoneshige, Azusa, Inoue, Takao, Wada, Akihiro, Kajiyama, Hiroshi, Takaoka, Yutaka, Sasaki, Kenroh, Ito, Akihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8892618/
https://www.ncbi.nlm.nih.gov/pubmed/35251340
http://dx.doi.org/10.3892/etm.2022.11200