Stable Fatty Acid Solvates of Dasatinib, a Tyrosine Kinase Inhibitor: Prediction, Process, and Physicochemical Properties

[Image: see text] Exploration of alternate solid forms for dasatinib, a potent oncogene tyrosine kinase inhibitor classified under Biopharmaceutics Classification System (BCS) class II drugs with low water solubility and high permeability, has been performed using COSMO-RS excess enthalpy (Hex) to i...

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Detalles Bibliográficos
Autores principales: Saladi, Venkata Narasayya, Kammari, Bal Raju, Maruthapillai, Arthanareeswari, Mahapatra, Sudarshan, Chennuru, Ramanaiah, Sajja, Eswaraiah, Rajan, Srinivasan Thirumalai, Mathad, Vijayavitthal T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8892647/
https://www.ncbi.nlm.nih.gov/pubmed/35252694
http://dx.doi.org/10.1021/acsomega.1c06753

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8892647/
https://www.ncbi.nlm.nih.gov/pubmed/35252694
http://dx.doi.org/10.1021/acsomega.1c06753

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