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Tumor bud-derived CCL5 recruits fibroblasts and promotes colorectal cancer progression via CCR5-SLC25A24 signaling

BACKGROUND: Tumor budding is included in the routine diagnosis of colorectal cancer (CRC) and is considered a tumor prognostic factor independent of TNM staging. This study aimed to identify the fibroblast-mediated effect of tumor bud-derived C–C chemokine ligand 5 (CCL5) on the tumor microenvironme...

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Detalles Bibliográficos
Autores principales: Gao, Ling-Fang, Zhong, Yan, Long, Ting, Wang, Xia, Zhu, Jia-Xian, Wang, Xiao-Yan, Hu, Zhi-Yan, Li, Zu-Guo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8892738/
https://www.ncbi.nlm.nih.gov/pubmed/35241150
http://dx.doi.org/10.1186/s13046-022-02300-w