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TADreg: a versatile regression framework for TAD identification, differential analysis and rearranged 3D genome prediction

BACKGROUND/AIM: In higher eukaryotes, the three-dimensional (3D) organization of the genome is intimately related to numerous key biological functions including gene expression, DNA repair and DNA replication regulations. Alteration of 3D organization, in particular topologically associating domains...

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Detalles Bibliográficos
Autor principal: Mourad, Raphaël
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8892791/
https://www.ncbi.nlm.nih.gov/pubmed/35236295
http://dx.doi.org/10.1186/s12859-022-04614-0