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TADreg: a versatile regression framework for TAD identification, differential analysis and rearranged 3D genome prediction
BACKGROUND/AIM: In higher eukaryotes, the three-dimensional (3D) organization of the genome is intimately related to numerous key biological functions including gene expression, DNA repair and DNA replication regulations. Alteration of 3D organization, in particular topologically associating domains...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8892791/ https://www.ncbi.nlm.nih.gov/pubmed/35236295 http://dx.doi.org/10.1186/s12859-022-04614-0 |