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A human-derived 3D brain organoid model to study JC virus infection

Progressive multifocal leukoencephalopathy (PML) is a frequent neurological complication in immunosuppressed patients. PML is caused by the JC virus (JCV), a neurotropic DNA polyomavirus that infects oligodendrocytes and astrocytes, causing inflammation and demyelination which lead to neurological d...

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Detalles Bibliográficos
Autores principales: Barreras, Paula, Pamies, David, Monaco, Maria Chiara, Muñoz, Laura S., Zhong, Xiali, Major, Eugene O., Hogberg, Helena T., Hartung, Thomas, Pardo, Carlos A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8892818/
https://www.ncbi.nlm.nih.gov/pubmed/35239145
http://dx.doi.org/10.1007/s13365-022-01062-7