Cargando…
Histone Deacetylase 6 Inhibition Restores Leptin Sensitivity and Reduces Obesity
The adipose tissue-derived hormone leptin can drive decreases in food intake while increasing energy expenditure. In diet-induced obesity, circulating leptin levels rise proportionally to adiposity. Despite this hyperleptinemia, rodents and humans with obesity maintain increased adiposity and are re...
| Autores principales: | , , , , , , , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2022
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8892841/ https://www.ncbi.nlm.nih.gov/pubmed/35039672 http://dx.doi.org/10.1038/s42255-021-00515-3 |