New Benzimidazole-, 1,2,4-Triazole-, and 1,3,5-Triazine-Based Derivatives as Potential EGFR(WT) and EGFR(T790M) Inhibitors: Microwave-Assisted Synthesis, Anticancer Evaluation, and Molecular Docking Study

[Image: see text] A new series of benzimidazole, 1,2,4-triazole, and 1,3,5-triazine derivatives were designed and synthesized using a microwave irradiation synthetic approach utilizing 2-phenylacetyl isothiocyanate (1) as a key starting material. All the new analogues were evaluated as anticancer ag...

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Detalles Bibliográficos
Autores principales: Hashem, Heba E., Amr, Abd El-Galil E., Nossier, Eman S., Anwar, Manal M., Azmy, Eman M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8892849/
https://www.ncbi.nlm.nih.gov/pubmed/35252706
http://dx.doi.org/10.1021/acsomega.1c06836

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8892849/
https://www.ncbi.nlm.nih.gov/pubmed/35252706
http://dx.doi.org/10.1021/acsomega.1c06836

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