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Reversible Conjugation of Non-ionic Detergent Micelles Promotes Partitioning of Membrane Proteins under Non-denaturing Conditions

[Image: see text] In the decades’-long quest for high-quality membrane protein (MP) crystals, non-ionic detergent micelles have primarily served as a passive shield against protein aggregation in aqueous solution and/or as a conformation stabilizing environment. We have focused on exploiting the phy...

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Detalles Bibliográficos
Autores principales: Lal, Mitra, Wachtel, Ellen, Sheves, Mordechai, Patchornik, Guy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8892955/
https://www.ncbi.nlm.nih.gov/pubmed/35179381
http://dx.doi.org/10.1021/acs.langmuir.1c03343