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flopp: Extremely Fast Long-Read Polyploid Haplotype Phasing by Uniform Tree Partitioning

Resolving haplotypes in polyploid genomes using phase information from sequencing reads is an important and challenging problem. We introduce two new mathematical formulations of polyploid haplotype phasing: (1) the min-sum max tree partition problem, which is a more flexible graphical metric compar...

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Detalles Bibliográficos
Autores principales: Shaw, Jim, Yu, Yun William
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8892958/
https://www.ncbi.nlm.nih.gov/pubmed/35041529
http://dx.doi.org/10.1089/cmb.2021.0436