Ero1α-Dependent ERp44 Dissociation From RyR2 Contributes to Cardiac Arrhythmia

Oxidative stress in cardiac disease promotes proarrhythmic disturbances in Ca(2+) homeostasis, impairing luminal Ca(2+) regulation of the sarcoplasmic reticulum (SR) Ca(2+) release channel, the RyR2 (ryanodine receptor), and increasing channel activity. However, exact mechanisms underlying redox-med...

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Detalles Bibliográficos
Autores principales: Hamilton, Shanna, Terentyeva, Radmila, Bogdanov, Vladimir, Kim, Tae Yun, Perger, Fruzsina, Yan, Jiajie, Ai, Xun, Carnes, Cynthia A., Belevych, Andriy E., George, Christopher H., Davis, Jonathan P., Gyorke, Sandor, Choi, Bum-Rak, Terentyev, Dmitry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8893133/
https://www.ncbi.nlm.nih.gov/pubmed/35086342
http://dx.doi.org/10.1161/CIRCRESAHA.121.320531

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8893133/
https://www.ncbi.nlm.nih.gov/pubmed/35086342
http://dx.doi.org/10.1161/CIRCRESAHA.121.320531

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