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Defective ORF8 dimerization in SARS-CoV-2 delta variant leads to a better adaptive immune response due to abrogation of ORF8-MHC1 interaction

In India, during the second wave of the COVID-19 pandemic, the breakthrough infections were mainly caused by the SARS-COV-2 delta variant (B.1.617.2). It was reported that, among majority of the infections due to the delta variant, only 9.8% percent cases required hospitalization, whereas only 0.4%...

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Detalles Bibliográficos
Autores principales: Chaudhari, Armi M., Singh, Indra, Joshi, Madhvi, Patel, Amrutlal, Joshi, Chaitanya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8893242/
https://www.ncbi.nlm.nih.gov/pubmed/35243596
http://dx.doi.org/10.1007/s11030-022-10405-9