A Dynamic Mass Redistribution Assay for the Human Sweet Taste Receptor Uncovers G-Protein Dependent Biased Ligands

The sweet taste receptor is rather unique, recognizing a diverse repertoire of natural or synthetic ligands, with a surprisingly large structural diversity, and with potencies stretching over more than six orders of magnitude. Yet, it is not clear if different cell-based assays can faithfully report...

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Detalles Bibliográficos
Autores principales: Servant, Nicole B., Williams, Mark E., Brust, Paul F., Tang, Huixian, Wong, Melissa S., Chen, Qing, Lebl-Rinnova, Marketa, Adamski-Werner, Sara L., Tachdjian, Catherine, Servant, Guy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8893300/
https://www.ncbi.nlm.nih.gov/pubmed/35250580
http://dx.doi.org/10.3389/fphar.2022.832529

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8893300/
https://www.ncbi.nlm.nih.gov/pubmed/35250580
http://dx.doi.org/10.3389/fphar.2022.832529

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