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Simultaneous cellular and molecular phenotyping of embryonic mutants using single-cell regulatory trajectories
Developmental progression and cellular diversity are largely driven by transcription factors (TFs); yet, characterizing their loss-of-function phenotypes remains challenging and often disconnected from their underlying molecular mechanisms. Here, we combine single-cell regulatory genomics with loss-...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cell Press
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8893321/ https://www.ncbi.nlm.nih.gov/pubmed/35176234 http://dx.doi.org/10.1016/j.devcel.2022.01.016 |