Neurofilament Light Chain Levels in Multiple Sclerosis Correlate With Lesions Containing Foamy Macrophages and With Acute Axonal Damage

BACKGROUND AND OBJECTIVES: To investigate whether white matter lesion activity, acute axonal damage, and axonal density in MS associate with CSF neurofilament light chain (NfL) levels. METHODS: Of 101 brain donors with MS (n = 92 progressive MS, n = 9 relapsing-remitting MS), ventricular CSF was col...

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Detalles Bibliográficos
Autores principales: van den Bosch, Aletta, Fransen, Nina, Mason, Matthew, Rozemuller, Annemieke Johanna, Teunissen, Charlotte, Smolders, Joost, Huitinga, Inge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8893592/
https://www.ncbi.nlm.nih.gov/pubmed/35241571
http://dx.doi.org/10.1212/NXI.0000000000001154

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8893592/
https://www.ncbi.nlm.nih.gov/pubmed/35241571
http://dx.doi.org/10.1212/NXI.0000000000001154

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