Cargando…
Neurofilament Light Chain Levels in Multiple Sclerosis Correlate With Lesions Containing Foamy Macrophages and With Acute Axonal Damage
BACKGROUND AND OBJECTIVES: To investigate whether white matter lesion activity, acute axonal damage, and axonal density in MS associate with CSF neurofilament light chain (NfL) levels. METHODS: Of 101 brain donors with MS (n = 92 progressive MS, n = 9 relapsing-remitting MS), ventricular CSF was col...
Autores principales: | van den Bosch, Aletta, Fransen, Nina, Mason, Matthew, Rozemuller, Annemieke Johanna, Teunissen, Charlotte, Smolders, Joost, Huitinga, Inge |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8893592/ https://www.ncbi.nlm.nih.gov/pubmed/35241571 http://dx.doi.org/10.1212/NXI.0000000000001154 |
Ejemplares similares
-
Post‐mortem multiple sclerosis lesion pathology is influenced by single nucleotide polymorphisms
por: Fransen, Nina L., et al.
Publicado: (2019) -
Neurofilament heavy chain side arm phosphorylation regulates axonal transport of neurofilaments
por: Ackerley, Steven, et al.
Publicado: (2003) -
Stress-Axis Regulation by Vitamin D(3) in Multiple Sclerosis
por: Rolf, Linda, et al.
Publicado: (2018) -
Progressive multiple sclerosis patients show substantial lesion activity that correlates with clinical disease severity and sex: a retrospective autopsy cohort analysis
por: Luchetti, Sabina, et al.
Publicado: (2018) -
Phosphorylation and compactness of neurofilaments in multiple sclerosis: Indicators of axonal pathology()
por: Petzold, Axel, et al.
Publicado: (2008)