Considerations for homology-based DNA repair in mosquitoes: Impact of sequence heterology and donor template source

The increasing prevalence of insecticide resistance and the ongoing global burden of vector-borne diseases have encouraged new efforts in mosquito control. For Aedes aegypti, the most important arboviral vector, integration rates achieved in Cas9-based knock-ins so far have been rather low, highligh...

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Detalles Bibliográficos
Autores principales: Ang, Joshua Xin De, Nevard, Katherine, Ireland, Rebekah, Purusothaman, Deepak-Kumar, Verkuijl, Sebald A. N., Shackleford, Lewis, Gonzalez, Estela, Anderson, Michelle A. E., Alphey, Luke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8893643/
https://www.ncbi.nlm.nih.gov/pubmed/35180218
http://dx.doi.org/10.1371/journal.pgen.1010060

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8893643/
https://www.ncbi.nlm.nih.gov/pubmed/35180218
http://dx.doi.org/10.1371/journal.pgen.1010060

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