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Considerations for homology-based DNA repair in mosquitoes: Impact of sequence heterology and donor template source
The increasing prevalence of insecticide resistance and the ongoing global burden of vector-borne diseases have encouraged new efforts in mosquito control. For Aedes aegypti, the most important arboviral vector, integration rates achieved in Cas9-based knock-ins so far have been rather low, highligh...
Autores principales: | Ang, Joshua Xin De, Nevard, Katherine, Ireland, Rebekah, Purusothaman, Deepak-Kumar, Verkuijl, Sebald A. N., Shackleford, Lewis, Gonzalez, Estela, Anderson, Michelle A. E., Alphey, Luke |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8893643/ https://www.ncbi.nlm.nih.gov/pubmed/35180218 http://dx.doi.org/10.1371/journal.pgen.1010060 |
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