Specificity of Loxosceles α clade phospholipase D enzymes for choline-containing lipids: Role of a conserved aromatic cage

Spider venom GDPD-like phospholipases D (SicTox) have been identified to be one of the major toxins in recluse spider venom. They are divided into two major clades: the α clade and the β clade. Most α clade toxins present high activity against lipids with choline head groups such as sphingomyelin, w...

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Detalles Bibliográficos
Autores principales: Moutoussamy, Emmanuel E., Waheed, Qaiser, Binford, Greta J., Khan, Hanif M., Moran, Shane M., Eitel, Anna R., Cordes, Matthew H. J., Reuter, Nathalie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8893692/
https://www.ncbi.nlm.nih.gov/pubmed/35180220
http://dx.doi.org/10.1371/journal.pcbi.1009871

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8893692/
https://www.ncbi.nlm.nih.gov/pubmed/35180220
http://dx.doi.org/10.1371/journal.pcbi.1009871

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