ACEA Attenuates Oxidative Stress by Promoting Mitophagy via CB1R/Nrf1/PINK1 Pathway after Subarachnoid Hemorrhage in Rats

METHOD: Endovascular perforation was performed to establish a SAH model of rats. ACEA was administered intraperitoneally 1 h after SAH. The CB1R antagonist AM251 was injected intraperitoneally 1 h before SAH induction. Adenoassociated virus- (AAV-) Nrf1 shRNA was infused into the lateral ventricle 3...

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Detalles Bibliográficos
Autores principales: Liu, Binbing, Tian, Yang, Li, Yuchen, Wu, Pei, Zhang, Yongzhi, Zheng, Jiaolin, Shi, Huaizhang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8894021/
https://www.ncbi.nlm.nih.gov/pubmed/35251464
http://dx.doi.org/10.1155/2022/1024279

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8894021/
https://www.ncbi.nlm.nih.gov/pubmed/35251464
http://dx.doi.org/10.1155/2022/1024279

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