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Cysteine Donor-Based Brain-Targeting Prodrug: Opportunities and Challenges

Overcoming blood-brain barrier (BBB) to improve brain bioavailability of therapeutic drug remains an ongoing concern. Prodrug is one of the most reliable approaches for delivering agents with low-level BBB permeability into the brain. The well-known antioxidant capacities of cysteine (Cys) and its v...

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Detalles Bibliográficos
Autores principales: Ni, Gaoyang, Hu, Zhenbiao, Wang, Ziteng, Zhang, Min, Liu, Xingyu, Yang, Guihong, Yan, Zhaowei, Zhang, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8894025/
https://www.ncbi.nlm.nih.gov/pubmed/35251474
http://dx.doi.org/10.1155/2022/4834117