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Cysteine Donor-Based Brain-Targeting Prodrug: Opportunities and Challenges
Overcoming blood-brain barrier (BBB) to improve brain bioavailability of therapeutic drug remains an ongoing concern. Prodrug is one of the most reliable approaches for delivering agents with low-level BBB permeability into the brain. The well-known antioxidant capacities of cysteine (Cys) and its v...
Autores principales: | Ni, Gaoyang, Hu, Zhenbiao, Wang, Ziteng, Zhang, Min, Liu, Xingyu, Yang, Guihong, Yan, Zhaowei, Zhang, Yang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8894025/ https://www.ncbi.nlm.nih.gov/pubmed/35251474 http://dx.doi.org/10.1155/2022/4834117 |
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