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Early Deletion of Neurod1 Alters Neuronal Lineage Potential and Diminishes Neurogenesis in the Inner Ear

Neuronal development in the inner ear is initiated by expression of the proneural basic Helix-Loop-Helix (bHLH) transcription factor Neurogenin1 that specifies neuronal precursors in the otocyst. The initial specification of the neuroblasts within the otic epithelium is followed by the expression of...

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Detalles Bibliográficos
Autores principales: Filova, Iva, Bohuslavova, Romana, Tavakoli, Mitra, Yamoah, Ebenezer N., Fritzsch, Bernd, Pavlinkova, Gabriela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8894106/
https://www.ncbi.nlm.nih.gov/pubmed/35252209
http://dx.doi.org/10.3389/fcell.2022.845461