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Early Deletion of Neurod1 Alters Neuronal Lineage Potential and Diminishes Neurogenesis in the Inner Ear
Neuronal development in the inner ear is initiated by expression of the proneural basic Helix-Loop-Helix (bHLH) transcription factor Neurogenin1 that specifies neuronal precursors in the otocyst. The initial specification of the neuroblasts within the otic epithelium is followed by the expression of...
Autores principales: | Filova, Iva, Bohuslavova, Romana, Tavakoli, Mitra, Yamoah, Ebenezer N., Fritzsch, Bernd, Pavlinkova, Gabriela |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8894106/ https://www.ncbi.nlm.nih.gov/pubmed/35252209 http://dx.doi.org/10.3389/fcell.2022.845461 |
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