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5-HT (2A) Receptor and 5-HT Degradation Play a Crucial Role in Atherosclerosis by Modulating Macrophage Foam Cell Formation, Vascular Endothelial Cell Inflammation, and Hepatic Steatosis

Aim: Previously, we found that diabetes-related liver dysfunction is due to activation of the 5-HT (2A) receptor (5-HT (2A) R) and increased synthesis and degradation of 5-HT. Here, we investigated the role of 5-HT in the development of atherosclerosis. Methods: The study was conducted using high-fa...

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Detalles Bibliográficos
Autores principales: Ma, Yingying, Liang, Xiurui, Li, Chen, Li, Ruoming, Tong, Xin, Zhang, Rui, Shan, Xuechun, Yang, Jing, Ma, Xiaonan, Lu, Wenjia, Li, Ruitong, Fu, Jihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japan Atherosclerosis Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8894120/
https://www.ncbi.nlm.nih.gov/pubmed/33536397
http://dx.doi.org/10.5551/jat.58305