Upstream open reading frames regulate translation of cancer-associated transcripts and encode HLA-presented immunogenic tumor antigens

BACKGROUND: Upstream open reading frames (uORFs) represent translational control elements within eukaryotic transcript leader sequences. Recent data showed that uORFs can encode for biologically active proteins and human leukocyte antigen (HLA)-presented peptides in malignant and benign cells sugges...

Descripción completa

Detalles Bibliográficos
Autores principales: Nelde, Annika, Flötotto, Lea, Jürgens, Lara, Szymik, Laura, Hubert, Elvira, Bauer, Jens, Schliemann, Christoph, Kessler, Torsten, Lenz, Georg, Rammensee, Hans-Georg, Walz, Juliane S., Wethmar, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8894207/
https://www.ncbi.nlm.nih.gov/pubmed/35239002
http://dx.doi.org/10.1007/s00018-022-04145-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8894207/
https://www.ncbi.nlm.nih.gov/pubmed/35239002
http://dx.doi.org/10.1007/s00018-022-04145-0

Ejemplares similares