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Upstream open reading frames regulate translation of cancer-associated transcripts and encode HLA-presented immunogenic tumor antigens

BACKGROUND: Upstream open reading frames (uORFs) represent translational control elements within eukaryotic transcript leader sequences. Recent data showed that uORFs can encode for biologically active proteins and human leukocyte antigen (HLA)-presented peptides in malignant and benign cells sugges...

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Detalles Bibliográficos
Autores principales:	Nelde, Annika, Flötotto, Lea, Jürgens, Lara, Szymik, Laura, Hubert, Elvira, Bauer, Jens, Schliemann, Christoph, Kessler, Torsten, Lenz, Georg, Rammensee, Hans-Georg, Walz, Juliane S., Wethmar, Klaus
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8894207/ https://www.ncbi.nlm.nih.gov/pubmed/35239002 http://dx.doi.org/10.1007/s00018-022-04145-0

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