Cargando…
Upstream open reading frames regulate translation of cancer-associated transcripts and encode HLA-presented immunogenic tumor antigens
BACKGROUND: Upstream open reading frames (uORFs) represent translational control elements within eukaryotic transcript leader sequences. Recent data showed that uORFs can encode for biologically active proteins and human leukocyte antigen (HLA)-presented peptides in malignant and benign cells sugges...
Autores principales: | Nelde, Annika, Flötotto, Lea, Jürgens, Lara, Szymik, Laura, Hubert, Elvira, Bauer, Jens, Schliemann, Christoph, Kessler, Torsten, Lenz, Georg, Rammensee, Hans-Georg, Walz, Juliane S., Wethmar, Klaus |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8894207/ https://www.ncbi.nlm.nih.gov/pubmed/35239002 http://dx.doi.org/10.1007/s00018-022-04145-0 |
Ejemplares similares
-
Somatic Functional Deletions of Upstream Open Reading Frame-Associated Initiation and Termination Codons in Human Cancer
por: Jürgens, Lara, et al.
Publicado: (2021) -
The Peptide Vaccine of the Future
por: Nelde, Annika, et al.
Publicado: (2021) -
Upstream open reading frames: Molecular switches in (patho)physiology
por: Wethmar, Klaus, et al.
Publicado: (2010) -
HLA Evolutionary Divergence as a Prognostic Marker for AML Patients Undergoing Allogeneic Stem Cell Transplantation
por: Roerden, Malte, et al.
Publicado: (2020) -
HLA-DR Presentation of the Tumor Antigen MSLN Associates with Clinical Outcome of Ovarian Cancer Patients
por: Tegeler, Christian M., et al.
Publicado: (2022)