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Uncover New Reactivity of Genetically Encoded Alkyl Bromide Non-Canonical Amino Acids

Genetically encoded non-canonical amino acids (ncAAs) with electrophilic moieties are excellent tools to investigate protein-protein interactions (PPIs) both in vitro and in vivo. These ncAAs, including a series of alkyl bromide-based ncAAs, mainly target cysteine residues to form protein-protein cr...

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Detalles Bibliográficos
Autores principales: Shu, Xin, Asghar, Sana, Yang, Fan, Li, Shang-Tong, Wu, Haifan, Yang, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8894327/
https://www.ncbi.nlm.nih.gov/pubmed/35252115
http://dx.doi.org/10.3389/fchem.2022.815991