LIM domain-wide comprehensive virtual mutagenesis provides structural rationale for cardiomyopathy mutations in CSRP3

Cardiomyopathies are a severe and chronic cardiovascular burden worldwide, affecting a large cohort in the general population. Cysteine and glycine-rich protein 3 (CSRP3) is one of key proteins implicated in dominant dilated cardiomyopathy (DCM) and hypertrophic cardiomyopathy (HCM). In this study,...

Descripción completa

Detalles Bibliográficos
Autores principales: Chauhan, Pankaj Kumar, Sowdhamini, Ramanathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8894373/
https://www.ncbi.nlm.nih.gov/pubmed/35241752
http://dx.doi.org/10.1038/s41598-022-07553-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8894373/
https://www.ncbi.nlm.nih.gov/pubmed/35241752
http://dx.doi.org/10.1038/s41598-022-07553-1

Ejemplares similares