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The m6A reader IGF2BP3 promotes acute myeloid leukemia progression by enhancing RCC2 stability

N6-methyladenosine (m6A) is the most abundant posttranscriptional modification of mRNA in eukaryotes. Recent evidence suggests that dysregulated m6A-associated proteins and m6A modifications play a pivotal role in the initiation and progression of diseases such as cancer. Here, we identified that IG...

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Detalles Bibliográficos
Autores principales: Zhang, Nan, Shen, Yan, Li, Huan, Chen, Ying, Zhang, Ping, Lou, Shifeng, Deng, Jianchuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8894383/
https://www.ncbi.nlm.nih.gov/pubmed/35217832
http://dx.doi.org/10.1038/s12276-022-00735-x