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Gene-based association tests using GWAS summary statistics and incorporating eQTL

Although genome-wide association studies (GWAS) have been successfully applied to a variety of complex diseases and identified many genetic variants underlying complex diseases via single marker tests, there is still a considerable heritability of complex diseases that could not be explained by GWAS...

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Detalles Bibliográficos
Autores principales: Cao, Xuewei, Wang, Xuexia, Zhang, Shuanglin, Sha, Qiuying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8894384/
https://www.ncbi.nlm.nih.gov/pubmed/35241742
http://dx.doi.org/10.1038/s41598-022-07465-0