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Single-cell transcriptomics links malignant T cells to the tumor immune landscape in cutaneous T cell lymphoma

Cutaneous T cell lymphoma (CTCL) represents a heterogeneous group of non-Hodgkin lymphoma distinguished by the presence of clonal malignant T cells. The heterogeneity of malignant T cells and the complex tumor microenvironment remain poorly characterized. With single-cell RNA analysis and bulk whole...

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Detalles Bibliográficos
Autores principales: Liu, Xiangjun, Jin, Shanzhao, Hu, Simeng, Li, Ruoyan, Pan, Haihao, Liu, Yi, Lai, Pan, Xu, Deshu, Sun, Jingru, Liu, Ziyang, Gao, Yumei, Zhao, Yifan, Liu, Fengjie, Xiao, Yu, Li, Yingyi, Wen, Yujie, Chen, Zhuojing, Xu, Bufang, Lin, Yuchieh, Ran, Menglong, Li, Qianxi, Yang, Shuxia, Li, Hang, Tu, Ping, Haniffa, Muzlifah, Teichmann, Sarah A., Bai, Fan, Wang, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8894386/
https://www.ncbi.nlm.nih.gov/pubmed/35241665
http://dx.doi.org/10.1038/s41467-022-28799-3