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Designing siRNA/chitosan-methacrylate complex nanolipogel for prolonged gene silencing effects

Despite immense revolutionary therapeutics potential, sustaining release of active small interfering RNA (siRNA) remains an arduous challenge. The development of nanoparticles with siRNA sustained release capabilities provides an avenue to enhance the therapeutic efficacy of gene-based therapy. Here...

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Detalles Bibliográficos
Autores principales: Cao, Ye, Tan, Yang Fei, Wong, Yee Shan, Aminuddin, Muhammad, Ramya, Bhuthalingam, Liew, Melvin Wen Jie, Liu, Jiaxin, Venkatraman, Subbu S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8894398/
https://www.ncbi.nlm.nih.gov/pubmed/35241750
http://dx.doi.org/10.1038/s41598-022-07554-0