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Designing siRNA/chitosan-methacrylate complex nanolipogel for prolonged gene silencing effects
Despite immense revolutionary therapeutics potential, sustaining release of active small interfering RNA (siRNA) remains an arduous challenge. The development of nanoparticles with siRNA sustained release capabilities provides an avenue to enhance the therapeutic efficacy of gene-based therapy. Here...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8894398/ https://www.ncbi.nlm.nih.gov/pubmed/35241750 http://dx.doi.org/10.1038/s41598-022-07554-0 |